Comparison of Oxycodone and Sufentanil for Preventing Catheter-Related Bladder Discomfort After Transurethral Resection of the Prostate: A Randomized, Double-Blind, Parallel-Group Controlled Trial

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: Oxycodone group:Oxycodone was used as the opioid for both anesthesia induction and maintenance;Sufentanil group:Sufentanil was used as the opioid for both anesthesia induction and maintenance; CONDITION: Benign Prostatic Hyperplasia; Catheter‐Related Bladder Discomfort PRIMARY OUTCOME: Incidence of moderate‐to‐severe CRBD within 6 hours postoperatively; SECONDARY OUTCOME: Analgesic rescue treatment;Rescue treatment for CRBD;Other adverse events;Excessive sedation;Incidence of moderate‐to‐severe CRBD at each time point;Emergence agitation;Overall incidence of CRBD at each time point;Respiratory depression;Postoperative pain severity;Patient satisfaction score;Postoperative nausea and vomiting;CRBD Severity Score; INCLUSION CRITERIA: 1.Male patients scheduled for elective transurethral resection of the prostate (TURP) or holmium laser enucleation of the prostate (HoLEP) under general anesthesia; 2.Aged 50–75 years; 3.Body mass inde X(BMI) between 18 and 28 kg/m2; 4.American Society of Anesthesiologists (ASA) physical status classification I or II; 5.Postoperative indwelling of a F20 three‐way urinary catheter;
Epistemonikos ID: dad936405f748618486dd72473bcbe1548ccce40
First added on: Jul 25, 2026