The Use of Intranasal Calcitonin to Improve Pain and Activity in Elderly Pelvic Ring Injuries

Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2019
Baseline: Treatment group will be prescribed 200IU of ISC daily for a period of 3 months. The control group will not be prescribed calcitonin. Participants will complete research only Iowa pelvis score questionnaire, SF‐36 questionnaire and visual analogue scale (VAS) to assess subjective pain and function. Two‐week follow up visit post discharge: participants will complete Iowa pelvis score questionnaire, SF‐36 questionnaire and VAS to assess subjective pain and function. Participants will be referred for a standard of care DEXA bone density scan if they have no previous diagnosis of osteoporosis and no history of previous scan within a year. Six weeks post discharge: participants will complete Iowa pelvis score questionnaire, SF‐36 questionnaire and VAS to assess subjective pain and function. Participants will undergo standard of care radiographic analysis of pelvic ring injury with AP/inlet and outlet pelvic x‐rays 4. Twelve weeks post discharge: Participants will complete Iowa pelvis score questionnaire, SF‐36 questionnaire and VAS to assess subjective pain and function. Participants will undergo standard of care radiographic analysis of pelvic ring injury with AP/inlet and outlet pelvic x‐rays ‐ Participants will perform a timed up and go (TUG) test. After informed consent is obtained, all patients who meet eligibility criteria will be randomized into one of two groups. Randomization will be achieved by numbering 50 sealed white envelopes (25 control, 25 treatment). There is no blinding to the randomization. It would be difficult to blind the participants, or the research personnel. We do not believe there will be any significant bias that can be corrected with blinding. Treatment: 200IUof ISC daily for a period of 3 month Control: Will not be prescribed calcitonin (ISC)
Epistemonikos ID: dab064e38d63a0d07a68df96caaa3430bdca4107
First added on: May 21, 2024