The role of umbilical cord serum therapy on corneal epithelial defect

INTERVENTION: Control: chloramphenicol and betamethasone eye drops every 6 hours, cycloplegic (homatropine) eye drop every 8 hours Intervention 1: Intervention: chloramphenicol and betamethasone eye drops every 6 hours, cycloplegic (homatropine) eye drop every 8 hours plus umbilical cord serum eye drop 20% every 4 hours. Intervention 2: Control: chloramphenicol and betamethasone eye drops every 6 hours, cycloplegic (homatropine) eye drop every 8 hours. Intervention: chloramphenicol and betamethasone eye drops every 6 hours, cycloplegic (homatropine) eye drop every 8 hours plus umbilical cord serum eye drop 20% every 4 hours Treatment ‐ Drugs CONDITION: corneal epithelial defect. ; Disorder of cornea, unspecified Disorder of cornea, unspecified PRIMARY OUTCOME: Measurement of corneal epithelial defect. Timepoint: days 3,5,7,12. Method of measurement: slit lamp. INCLUSION CRITERIA: INCLUSION CRITERIA: Diabetic patients with corneal epithelial defect following diabetic vitrectomy at labbafinejad hospital. Exclusion criteria: 1) Any history of Eye herpes infection, Refractive surgery, Autoimmune disease, Immune defficiency; 2) patients with one eye 3) use of any eye drops except Chloramphenicol, Betamethasone, Cycloplegic and contact lens for corneal epithelial defect.