Cognitive-behavioral stress management decreases dysphoric mood and herpes simplex virus-type 2 antibody titers in symptomatic HIV-seropositive gay men

The requested reference [d7c9860cbe9c547a1e943584b86b48dd1e5473ff] no longer exists in our database. It has been replaced by the current reference: [51c632aeff900d42c712da0b3be5c378408c7bb8]

Authors Lutgendorf, SK, Antoni, MH, Ironson, G, Klimas, N, Kumar, M, Starr, K -More
Category Primary study
JournalJournal of Consulting and Clinical Psychology
Year 1997
Links Pubmed, DOI
This study tested the effects of a 10‐week group cognitive‐behavioral stress management (CBSM) intervention on mood and immunologic parameters in HIV‐seropositive gay men whose disease had progressed to a symptomatic stage. Men were randomized to either CBSM or a modified waiting‐list control group. The CBSM intervention significantly decreased self‐reported dysphoria, anxiety, and total distress. Individuals who practiced relaxation more consistently had significantly greater drops in dysphoria. The intervention also decreased herpes simplex virus‐Type 2 (HSV‐2) immunoglobulin G antibody titers. The control group showed no significant changes in either mood or antibody titers. Individual difference analyses revealed that decreases in dysphoria significantly predicted lower HSV‐2 antibody titers by the end of the 10‐week period. Neither group displayed changes in HSV‐Type 1 antibody titers or in CD4+ or CD8+ cell numbers.
Epistemonikos ID: da79a6531ec5c285133d3e0b200ba922de9105c7
First added on: Dec 01, 2013