Use of honey in diabetic foot ulcer: Systematic review and meta-analysis.

OBJECTIVE: The aim of this study was to evaluate the role of honey dressing as an effective intervention for diabetic foot wound management and to provide a reliable basis for future clinical study. MATERIALS AND METHODS: We analyzed an assortment of randomized controlled trial (RCT), quasi-experimental and cross-sectional studies. We selected RCTs and quasi-experimental studies for meta-analysis. We only conducted a descriptive analysis for observational studies. RESULTS: The meta-analysis showed that honey used effectively reduces wound recovery time and rate, incurred pain, hospital stay, and accelerates granulation in DFU wounds. CONCLUSIONS: Our findings suggest that honey effectively promotes healing in DFU. Further research is needed to elucidate these findings so that this form of treatment can be widely applied.