Effect of a Self-Efficacy Focused Intervention on Skin Toxicity, Self-Management, and Quality of Life in Lung Cancer Patients Receiving Targeted Therapy A Randomized Controlled Trial

Authors
Category Primary study
Registry of TrialsThai Clinical Trials Registry
Year 2026
INTERVENTION: Experimental Behavioral,Active Comparator Other Participants receive a structured educational and supportive care program according to study protocol. Duration: 16 weeks. Mode of delivery: Face to face sessions and telephone or online support. Content: The program includes education video learning feedback and problem solving. Participants perform self care regularly. The program improves self efficacy and reduces dermatologic adverse events.,Participants receive standard oncology care according to institutional guidelines. Duration: 16 weeks.Mode of delivery: Routine clinical care during scheduled visits. Content: Usual care includes routine follow‐up, symptom assessment, and general education on medication use and skin care. No structured self‐efficacy‐based intervention or continuous follow‐up support is provided. Self efficacy based intervention,Usual care CONDITION: Lung cancer; EGFR TKI; Skin toxicity; Self efficacy; Self management; Quality of life; Randomized controlled trial Non small cell lung cancer Dermatologic adverse events ; Lung cancer; EGFR TKI; Skin toxicity; Self efficacy; Self management; Quality of life; Randomized controlled trial PRIMARY OUTCOME: Skin toxicity severity Baseline Week 8 Week 16 CTCAE version 5.0 SECONDARY OUTCOME: Self efficacy Baseline Week 8 Week 16 SUPPH scale,Self management Baseline Week 8 Week 16 SC CII version 2.0,Quality of life Baseline Week 8 Week 16 DLQI INCLUSION CRITERIA: 1. Age 18 years or older 2. Confirmed diagnosis of EGFR mutation positive advanced non small cell lung cancer Receiving EGFR tyrosine kinase inhibitor therapy for at least 4 weeks 3. Presence of dermatologic adverse events related to treatment 4. Ability to communicate and provide informed consent
Epistemonikos ID: d9d235f53ce9bb84f660f90ac6c9f6a60ec7b886
First added on: Aug 08, 2026