ZYNRELEF vs Continuous Catheter for Pain Management Following Shoulder Arthroplasty

Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2025
The purpose of this study is to determine if local intra-operative application of ZYNRELEF (topical medication) during shoulder replacement surgery improves pain control (as defined by opioid consumption after surgery) compared to the use of an interscalene block with catheter. This is a randomized clinical trial without blinding. Subjects will complete patient reported outcomes before and after surgery. Subjects will track their narcotic use, pain scores and pain satisfaction after surgery.
Epistemonikos ID: d994335d48b1d4b31621b76db8b0954a0590985c
First added on: Dec 13, 2025