Mind-body interventions in patients with multiple sclerosis

INTERVENTION: The patients included in the hypnoanalysis group should assist to 11 sessions which consisted in 1 interview and 10 hypnotic sessions that lasted around 1 hour (1 weekly) performed as follow: 1) the first day consisted in a semi‐structured interview of questions related with their life, before, during and after the diagnosis, a possible emotional cause of the disease and impressive events before the disease; 2) the second session was performed in hypnosis and consisted in the search in the “book of their lifeâ€? of at least for 5 events related with the cause of the disease and in the restructuring of at least one of the events that apparently still affected the patient, these restructuring was based in the reimprinting technique described by Dilts et al.(this technique consisted in modify the traumatic scene by identifying the resources that the patients and the others involved ones needed, and changing the possible beliefs created in the event); 3) the third session consisted in calling the responsible part of the disease and asking it for the cause(s) of the disease and possible solutions of it and repeat each possible solution 100 times in their mind and if they agreed they made a commitment with that part to change in that aspects; 4) the fourth day consisted in talking with the inner child and with their perfect or ideal version and asking them what they needed to be happy (in the case of the child) and to be like them (in the case of their perfect version) and they made a commitment with both parties to change what they ask for, finally they performed a final fusion among them and the child and the perfect version; 5) the fifth session consisted in searching in the book of healing for all possible actions that will lead to the physical improvement of disease and repeat them 100 times; 6) the sixth session consisted in a script related to mind‐body interconnection based in a script of Satir ; 7) the seventh session consisted in a script that gave them to a motiv CONDITION: Multiple sclerosis; ; Multiple sclerosis Neurological ‐ Multiple sclerosis PRIMARY OUTCOME: For primary caregivers: The Zarit burden inventory[This variable was measured 1 week before the first intervention and 1‐2 weeks after the last intervention and 3 months later] Patient functionality measured by the expanded disability status scale. [this variable was measured 1 week before the first intervention and 1‐2 weeks after the last intervention and in a follow up 3 months later.] the primary caregivers were measured for anxiety state and trait with the State‐Trait Anxiety Inventory (STAI) [this variable was measured 1 week before the first intervention and 1‐2 weeks after the last intervention and 3 months later.] SECONDARY OUTCOME: The quality of life measured with the short form 36 health questionnaire, SF‐36[this variable was measured 1 week before the first intervention and 1‐2 weeks after the last intervention and in a follow up 3 months later.] INCLUSION CRITERIA: Patients older than 18 years Patients with multiple sclerosis diagnosed with the McDonald criteria Patients with walking limitation, with at least 6 points in the Expanded disability status scale (EDSS score equal or more than 6) Patients that want voluntarily participate in the study