A Multicenter randomized folic acid-controlled clinical trial of traditional Chinese herbal medicine and Moluo Dan in the treatment of gastric precancerous lesion

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2008
INTERVENTION: Group C:Moluo Dan, 9g, taken orally, Tid;Group A:Folic acid, 5mg, taken orally, Tid;Group B:TCM "Bianzhen", 100‐150ml once orally, Tid; CONDITION: Gastric precancerous lesion (gastric epithelial dysplasia of mild or moderate degree at the base of chronic atrophic gastritis) PRIMARY OUTCOME: Incidence rate of gastric cancer;Histopathological score of gastric mucos; SECONDARY OUTCOME: Mucosal lesion score under endoscopy;Symptom score;Score of Patient reported outcome instrumen; INCLUSION CRITERIA: 1. Outpatient or inpatient fulfilling the diagnosis of gastric precancerous lesion by gastro‐endoscopy and histopathology; 2. Fulfilling the traditional Chinese medicine diagnosis of liver‐stomach disharmony syndrome, stomach‐yin insufficiency syndrome, spleen‐stomach damp‐heat syndrome, qi stagnation and spleen deficiency syndrome; 3. Age of 18–70, both males and females; 4. With informed written consent.
Epistemonikos ID: d92c5c89c8209b3f83288248523c87d379b66236
First added on: Aug 21, 2024