Clinical trial of homeopathic medicine arsenic album as add on therapy in hospitalized patients admitted with Covid 19 disease

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2020
INTERVENTION: Intervention1: Arsenicum album: Arsenicum album Homeopathic medicine in 30x 200 and 1m potency (Doses as per Homeopathic Pharmacopia) Control Intervention1: Standard line treatment for Covid 19: Antivirals like Remdesvir, Fabiflu Antibiotics as monocef, piptaz, meropenem Steroids like Methylprednisone, Hydrocortisone Immunosupressants like tocilizumab CONDITION: Health Condition 1: B972‐ Coronavirus as the cause of diseases classified elsewhere PRIMARY OUTCOME: Proportion of patients achieving viral clearance or symptoms free within 28 days, upon administration of treatment for 28 days in patients. ; 1 by doing investigations of inflammatory markers ; 2 weaning from ventilation ; 3 weaning oxygen of patientsTimepoint: Assessment on daily basis, and investigatory assessment on 1st day, 4th day, 7th day, 11th day and on discharge. SECONDARY OUTCOME: 1) Proportion of patients showing improvement in clinical condition as defined by WHO ordinal scale of clinical improvement in patients on day5, day10, day15, day20,day25 and day 28. ; 2) Time to wean of oxygen supply (time to return to normal or baseline oxygen saturation) in patients within 28 days. ; 3) Proportion of patients requiring invasive ventilator within 28days. ; 4) Proportion of patients with mortality within 28 days in patients. ; Timepoint: on 1st day of admission then 4th day, 7th day, 11th day and on discharge day. INCLUSION CRITERIA: 1) Subjects male or female age 18 to 75 years. 2) Laboratory confirmed cases of sars‐cov‐2 positive 3) Signs of respiratory failure requiring oxygen therapy 4) Negative results for pregnancy 5) Subjects or relatives are willing and capable of signing the consent.
Epistemonikos ID: d8fc7d383a1b6471d19afee08f1511f282160449
First added on: Nov 07, 2020