Cardiac Preconditioning Effect of Remote Ischemia and Nicorandil in Patients Undergoing Elective Percutaneous Coronary Intervention

Authors
Category Primary study
Registry of TrialsUMIN Clinical Trials Registry
Year 2011
INTERVENTION: Control: Subjects who do not undergo any pre‐treatment before PCI. RIPC: Subjects who undergo RIPC pre‐treatment induced by three 5‐minute inflations of a blood pressure cuff to 200mmHg around the upper arm, followed by 5‐minute intervals of reperfusion 1 hour before PCI. Nicorandil: Subjects who undergo intravenous 4mg Nicorandil administration as a bolus 1 hour before PCI, followed by 6mg/hour. CONDITION: Patients with stable myocardial ischemia who undergo elective PCI. PRIMARY OUTCOME: The ratio of patients with acute myocardial infarction associated with PCI employing the 2007 universal definition by the joint ESC‐AHA‐ACC‐WHF task force. SECONDARY OUTCOME: 1. Ischemic event during PCI and 8 months MACE after PCI procedure; 2. safety of RIPC and Nicorandil INCLUSION CRITERIA: 1. Silent myocardial ischemia or stable angina pectoris patient. 2. Over 20 years old patient.
Epistemonikos ID: d82adca825e52ece03c32c41697e441a75350e2d
First added on: Aug 22, 2024