CoKnie

INTERVENTION: Daily supplementation of hydrolysed collagen (10g) or placebo (maltodextrin; 10g), for a period of 12 weeks. All supplements will be provided as flavoured powder drink products that can be dissolved in water. CONDITION: Osteoarthritis, Knee ; ; PRIMARY OUTCOME: The primary objective is to investigate the difference between the two groups in change from baseline in Oxford Knee Scores at 6 weeks after the surgery. SECONDARY OUTCOME: Secondary objectives are to assess the difference between the two groups ; in change from baseline in Oxford Knee Scores at 12 weeks after the surgery and at 6 months after the surgery. ; ; On pain VAS scores measured at hospital admission, 2 weeks post‐surgery, and 6 weeks post‐surgery. ; ; On the amount and period of pain relieving therapies, ; On inflammation in synovial fluid, muscle and knee function, functional tests and clinical outcome parameters. ; INCLUSION CRITERIA: Planned for total knee replacement therapy > 18 years old and mentally competent