Effect of Intradialytic Exercise on Serum FGF23 Levels and left ventricular structure and function in Hemodialysis Patients: : A randomized controlled trial pilot study

INTERVENTION: exercise ,no exercise exercise,conventional hd without exercise Experimental Behavioral,No Intervention Other CONDITION: esrd patient on hd ; intradialytic exercise , esrd on hd ,fgf 23 intradialytic exercise , esrd on hd ,fgf 23 PRIMARY OUTCOME: fgf23 level 6 months serum fgf23 level,Fibroblast Growth Factor 23 6 months serum Fibroblast Growth Factor 23 SECONDARY OUTCOME: lief 6 months echocardiogram,left ventricular ejection fraction 6 months echocardiogram,left ventricle mass 6 months echocardiogram INCLUSION CRITERIA: 1.Adults aged 18‐85 years 2.On maintenance hemodialysis for at least 3 months 3.Able to perform exercise during dialysis