Compare the effects of reflexology and relaxation on physical and mental symptom multiple sclerosis

INTERVENTION: In the experimental groups were performed foot reflexology and relaxation intervention (Jacobson and Benson) within 4 weeks, twice a week for 40 minutes Intervention 1: In the experimental groups were performed foot reflexology and relaxation intervention (Jacobson and Benson) within 4 weeks, twice a week for 40 minutes. Intervention 2: The control group was received only care and routine medical treatment as directed by a doctor. The control group was received only care and routine medical treatment as directed by a doctor. Treatment ‐ Drugs Treatment ‐ Other CONDITION: Demyelinating diseases of the central nervous system G35‐G37 multiple sclerosis. ; Demyelinating diseases of the central nervous system PRIMARY OUTCOME: Mmental symptoms (stress ,anexity , depression). Timepoint: Before, immediately and two months after interventions. Method of measurement: Questionnaire. Physical symptoms (pain,fatigue). Timepoint: Before, immediately and two months after interventions. Method of measurement: Questionnaire. INCLUSION CRITERIA: Inclusion criteria : Women aged 18‐50 years suffering from MS (relapsing‐remitting, primary progressive and secondary progressive); MS final diagnosis by neurologists based on McDonald criteria with the elapse of at least 6 months from relevant diagnosis; tendency to participate in the research; no previous participation at treatment sessions of complementary medicine methods such as reflexology, relaxation, massage for the last 6 months; to feel chronic pain in at least one body organs, previous use of pain medication and Numerical Rating Scale (NRS); having the fatigue severity score of equal to and over 4 based on fatigue severity scale( FSS); have high scores of depression (more than 13), anxiety (more than 9) and stress (more than 18) based on DASS‐21 scale; acquisition of scores 0‐5.5 based on the Expanded Disability Status Scale( EDSS); not being in the menstruation period, nonexistence of deformity, callus or corn in the feet, feet lesion or cleft,