Hypoglycorrhachia lymphocytic meningoencephalitis: beyond tuberculosis, consider neurobrucellosis.

INTRODUCTION: Brucellosis, a common zoonotic infection caused by bacteria of the genus Brucella, is prevalent in many countries around the world. Neurobrucellosis can develop at any stage of the disease and present with a variety of symptoms. This study aims to emphasize the importance of considering this diagnosis in cases of chronic meningoencephalitis when brucellosis exposure is a possibility. PATIENTS AND METHODS: We present the case of a 65-year-old farmer with a two-month history of chronic meningoencephalitis. Results. The results of the lumbar puncture, magnetic resonance imaging, and most importantly, serology, led to a diagnosis of neurobrucellosis. The patient responded well to dual antibiotic therapy, with regression of neurological signs and a return to independence. CONCLUSION: Although rare, brucellosis should remain in the differential diagnosis for hypoglycorrhachia lymphocytic meningitis, particularly in endemic regions.