Intrahepatic cholestasis of pregnancy in second trimester. case report

Intrahepatic cholestasis is the most common liver disease of pregnancy. It occurs predominantly in the third trimester, its incidence is between 0,2% and 2% and varies depending on geographical location, ethnic group, maternal age, gestations, previous history of hepatitis C, biliary diseases, environmental and genetic factors. We present a female patient of 26 years, with a pregnancy of 25 weeks of gestation, which manifests pruritus of 14 days of evolution originating in palms and plants, which is generalized;concomitantly presents abdominal pain in upper right quadrant of 4 days of evolution, mild intensity and colic character. Laboratory tests report: aspartate aminotransferase: 53 U/L, alanine aminotransaminase:84 U/L, confirming diagnosis.