Meta analysis of the efficacy and safety of neurogenic bladder after acupuncture treatment of spinal cord injury

Objective: Evaluate the efficacy and safety of neurogenic bladder after acupuncture treatment of spinal cord injury to provide guidance and basis for clinic.Method: Computer retrieval PubMed, EMBASE, Cochrane Clinical Controlled Trial Registration Database, China Knowledge Database, Vip Database, Chinese Biomedical Documentation Database, China Retrieving time to build the library until July 2016, obtaining a link with A randomized controlled trial related to neurogenic bladder after acupuncture treatment of spinal cord injury, using RevMan5.3 software for data analysis. Descriptive analysis could not be used when data merge compared to the control group. Bladder residue urine volume (Urinary Flow Dynamics Detection Subgroup: MD=- 36.91,95% CI=-41.08 - -32.75, P^0.000 01.B Supertest Subgroup: MD=-27.07,95% CI=-34.48 - -19.66, P^0.000 01..Diagroup: MD=-25.6,95% CI=-47.24~-3.96, P=0.02) .2) with control group Compared to the acupuncture treatment group, the maximum bladder capacity can be significantly increased (Urinary Flow Dynamics Detection Subgroup: MD=53.38,95% CI=43.48 to 63.28, P≈ 0.000 01.B Supertest Subgroup: MD=51.99,95% CI=36.91-67.08, P^0.000 01; Guided Urinary subgroup: MD=0.4=0.4=0.4=32,95% CI = -41.28 to 114.12, P=0.36) .3) Acupuncture treatment group increased urethra closure pressure (MD=7.04,95% CI=4.92~9.16, P^0.000 1) .4) compared to the control group, acupuncture treatment group improved bladder responsiveness (MD=0.89,95% CI=0.53~ 1.25, P/ 0.000 1) .5) A significant decrease in average daily incontinence in the acupuncture treatment group compared to the control group (MD=-1.89,95% CI=-2.15~-1.63, P¥0.000 1) .6) a significant increase in average daily urination in the acupuncture treatment group compared to the control group (MD=61.37,95% CI=49.57~ 3.18, P^0.000 1) .7) A significant increase in the effectiveness of treatment in the acupuncture treatment group compared to the control group (RR=1.48,95% CI=1.31- 1.68, P0.000 1) .8) The difference in the incidence of adverse events in the acupuncture treatment group compared to the control group was not statistically significant (RR=0.37,95% CI=0.1- 0.1- 1.36, P=0.37,90.13). conclusion: acupuncture treatment alone Applied or acupuncture treatment as adjuvant therapy, combined with other treatments for neurogenic bladder after spinal cord injury has some effectiveness and safety. It can reduce bladder residue, average daily incontinence, increase the maximum volume of bladder, urethra closure pressure and daily average urination, overall improvement of bladder function., due to the low quality and evidence strength of incorporation studies and the heterogeneity of interstudies, part of Analysis results need to be treated with caution, and a large number of high-quality randomized controlled trials are still required for further analysis to yield more accurate conclusions and provide guidance and basis for clinical treatment.