The effect of nalbuphine combined with ropivacaine on the analgesic duration of iliac fascia block in total knee arthroplasty under ultrasound guidance

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: Group N:Perform FICB under ultrasound guidance. The local anesthetic used is 30 ml of 0.33% ropivacaine plus 10 mg of nalbuphine injection.;Group R:Under ultrasound guidance, FICB was performed using 30 ml of 0.33% ropivacaine as the local anesthetic.; CONDITION: Osteoarthritis of knee PRIMARY OUTCOME: The sensory effect time of the femoral nerve and the lateral femoral cutaneous nerve;Duration of sensory perception of the femoral nerve and the lateral femoral cutaneous nerve;The total amount of 24h patient‐controlled intravenous analgesia pump used;Resting VAS score and passive movement VAS score were measured at 8h, 12h, 16h, 20h, 24h and 48h after surgery; SECONDARY OUTCOME: The first time to press the patient‐controlled intravenous analgesia pump;VAS scores at 8h (T1), 12h (T2), 16h (T3), 20h (T4), and 24h (T5) after completion of block;Number of cases requiring remedial analgesics within 24 hours after block (cases);HSS scores before operation, at 1 day and 5 days after operation;Time to get out of bed for activities; INCLUSION CRITERIA: 1. Patients diagnosed with knee osteoarthritis and scheduled for total knee arthroplasty (TKA) surgery; 2. Age between 65 and 85 years old, regardless of gender; 3. Body Mass Inde X(BMI) ranging from 18.5 to 30 kg/m^2; 4. American Society of Anesthesiologists (ASA) classification of grades I to III; 5. Voluntary and have signed the informed consent form.
Epistemonikos ID: d5454acfc40dadf141e3c479dd903016bc8e3afe
First added on: Oct 08, 2026