A study on the effects of Co enzyme Q 10 on improving semen quality.

INTERVENTION: • The study will be carried out at a tertiary care reproductive health centre (Vindana Reproductive Health centre) • Sixty patients with idiopathic asthenozoospermia with normal sperm concentration will be recruited for the study. • Following random allocation 30 patients will be treated with Co enzyme Q 10 (Ubiquinone) 90 mg/day for 3 months duration. • The control group will also be treated with a placebo (An inert capsule) for same duration. CONDITION: Male Subfertility PRIMARY OUTCOME: Change of sperm motility as assessed by seminal fluid analysis (SFA) SECONDARY OUTCOME: Change of sperm concentration and sperm morphology as assessed by seminal fluid analysis (SFA) INCLUSION CRITERIA: 1. Male partners who are diagnosed to have male factor sub fertility seeking treatment at a tertiary care treatment centre 3.Age 20‐45 years 4. Base line seminal fluid parameters with sperm total motility <40%, sperm concentration >15*10^6 /ml, normal morphology >4%