In colorectal metastases patients who require liver resection, does a surgeon having knowledge of liver fat measurements influence surgical planning decisions that result in improved patient outcomes.

Authors
Category Primary study
Registry of TrialsANZCTR
Year 2015
INTERVENTION: Intervention arm – the surgeon will have knowledge of a quantitative measure of liver fat from MRI (HepaFat‐Scan) CONDITION: Resection of colorectal liver metastases PRIMARY OUTCOME: Primary Outcome 1: all cause mortality as assessed by data linkage to medical records Primary Outcome 2: postoperative complications as assessed by data linkage to medical records (e.g. ascites, urine infection, bilioma, renal failure) Primary Outcome 3: deviations from standard surgical treatment as assessed by qualitative questionnaire designed specifically for this study SECONDARY OUTCOME: Secondary Outcome 1: all cause mortality as assessed by data linkage to medical records Secondary Outcome 2: hospital stay as assessed by data linkage to medical records Secondary Outcome 3: intraoperative blood loss as assessed by data linkage to medical records Secondary Outcome 4: level of histopathologic steatosis as assessed by a visual inspection of a liver biopsy specimen by a pathologist Secondary Outcome 5: histopathologic steatosis (percentage area of fat occupying the slide) as assessed by computer assisted morphometric image analysis of a Masson trichrome stained liver biopsy section Secondary Outcome 6: liver functional status as assessed by standard liver biochemical assays INCLUSION CRITERIA: colorectal liver metastases requiring liver resection, abdominal MRI with HepaFat‐Scan (acquired after enrollment)
Epistemonikos ID: d302330eaf67508231e488dec4c4f6013ab98f5f
First added on: Aug 25, 2024