The of aquatic exercise interventions on quality of sleep, mental toughness, cognitive function, fatigue, paresthesia and depression among patients with Multiple Sclerosis (MS)

INTERVENTION: Intervention 1: Intervention group: The experimental group will perform an aquatic exercise in 8 weeks and in every week 3 sessions of 60 minutes that will be conducted under a trained and professional instructor of aquatic exercising and it includes a set of warming‐up, stretching, balance and coordination exercises, endurance and strengths training in the pool. Intervention 2: Control group: The control group will not receive any interference. CONDITION: MS. ; Multiple sclerosis PRIMARY OUTCOME: Depression. Timepoint: The beginning of the study (baseline), week four and end of the study (week eight). Method of measurement: Beck Depression Inventory (BDI). Fatigue. Timepoint: The beginning of the study (baseline), week four and end of the study (week eight). Method of measurement: Fatigue Severity Scale (FSS). Mental toughness. Timepoint: The beginning of the study (baseline), week four and end of the study (week eight). Method of measurement: Mental toughness questionnaire (MTQ48). Neurological performance. Timepoint: The beginning of the study (baseline), week four and end of the study (week eight). Method of measurement: StroopTest and NUCog test. Paresthesia. Timepoint: The beginning of the study (baseline), week four and end of the study (week eight). Method of measurement: Visual Analogue Scale(VAS). Quality of sleep. Timepoint: The beginning of the study (baseline), week four and end of the study (week eight). Method of measurement: Insomnia Severity Index (ISI). INCLUSION CRITERIA: Diagnosis of MS by neurologist; Female gender; Age 18‐65 years; EDSS 0‐6; No diagnosed cardiovascular diseases; No metabolic disorders; Psychiatric disorders and orthopedically diseases; No comorbid with other neurological diseases ; Willing and able to comply with the study conditions; Written informed consent.