GEO 002: Is a reduction in urate levels the mechanism by which allopurinol improves endothelial function?

Authors
Category Primary study
Registry of TrialsISRCTN registry
Year 2006
INTERVENTION: Probenecid 1000 mg versus placebo CONDITION: Chronic Heart Failure ; Circulatory System ; Chronic Heart Failure PRIMARY OUTCOME: Forearm blood flow SECONDARY OUTCOME: 1. Oxidative stress burden; 2. Urate levels INCLUSION CRITERIA: 1. Three‐month period free of hospitalisations prior to screening 2. Ability to give written informed consent to participate in the study 3. Diagnosis of mild to moderate chronic heart failure
Epistemonikos ID: d2c16d1b3fbcad3fb844d38d4ed00d37542250ec
First added on: Aug 21, 2024