Assessment of quality of life (QOL) improvement by moisturizer to radiation dermatitis accompanying radiation therapy after breast conserving surgerysurgery

INTERVENTION: Moisturizing agent application group Heparinoid cream From start of radiation therapy Twice daily Using 1FTU on irradiated skin Non moisturizing agent application group No use of any moisturizing cream and topical creams during radiation therapy on irradiated skin. CONDITION: Breast cancer Radiation dermatitis PRIMARY OUTCOME: DLQI total scores at a week after treatment completion SECONDARY OUTCOME: DLQI total score; DLQI subscale; NCI‐CTCAE Grade (radiation dermatitis); Use of steroid cream INCLUSION CRITERIA: 1)Patients planning to conduct radiation therapy after breast‐conserving surgery at our hospital radiotherapy department at a dose of less than a divided dose (dose: 2.66 Gy / day total dose 42.56 Gy irradiation energy: 4 MV or 6 MV) (whether or not boost irradiation is asked Absent) 2)Patients who can understand the Japanese DLQI question and can answer 3)When assigned to a non‐moisturizing group, patients who can agree not to apply moisturizing agent for a fixed period 4)Women with age from 40 to 80 who have skin dryness symptoms and a heparin analog containing preparation is indicated 5)Patients who got an explanation about the contents of this research and gained consent in writing about research participation