Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and Prostate

The COMFORT study will evaluate an artificial intelligence-based platform developed to support the clinical assessment of kidney and prostate cancer. The platform utilises imaging data to provide AI-generated outputs intended to assist clinicians in the assessment of suspected lesions. The primary objective of the study is to assess the role of the COMFORT platform in the clinical decision making process of clinicians managing kidney or prostate cancer cases. Secondary objectives include evaluation of the performance of AI models on anatomical segmentations, tumor characterisation (localisation, volumetric measurements, lesion classification, and scoring (e.g., Bosniak, PI-RADS, RENAL). Also the acceptability, usability, utility and trustworthiness of the AI models will be evaluated. In addition, potential causes of privacy leakage associated with the COMFORT AI models will be evaluated as part of the platform\'s privacy assessment.