Translocation (5;19)(q13;q13) in a multinodular thyroid goiter.

Category Primary study
JournalCancer genetics and cytogenetics
Year 1995
We describe the cytogenetics of a multinodular thyroid goiter where 90% of the analyzed cells showed a diploid karyotype with a balanced translocation between chromosomes 5 and 19: 46,XX,t(5;19)(q13;q13). This translocation has been previously described in cases of thyroid adenoma. Our case is the first report of this anomaly in nodular hyperplasia. We discuss its putative role in the neoplastic transformation of thyroid lesions.
Epistemonikos ID: d172f26225a991384965fd5168483710f5be1320
First added on: Apr 14, 2022