Pancreatic duct strictures; biodegradable self-expandable versus plastic stents, a randomized trial

Authors
Category Primary study
JournalOverview of Medical Research in the Netherlands
Year 2017
INTERVENTION: Randomisation between endoscopic placement of a biodegradable self expandable stent or plastic stent to treat a fibrotic pancreatic duct stricture CONDITION: Chronic pancreatitis, Pancreatic duct strictures ; ; PRIMARY OUTCOME: The primary outcome measure is the number of therapeutic interventions during the 24 months follow‐up period (defined as therapeutic endoscopic procedures related to the pancreatic duct stricture or pancreatic pain (ERCP, insertion of feeding tubes) and surgical procedures.; SECONDARY OUTCOME: 1. Clinical success, defined as no need for further PD drainage after stent extraction or resolution. ; ; 2. Complications. ; ; 3. Pain relief, defined as complete; Izbicki score <10, or partial; >50% decrease. ; ; 4. Stricture recurrence, defined as need for a re‐intervention for a PD stricture after stent extraction or resolution. ; ; 5. Conversion to surgery. ; INCLUSION CRITERIA: Chronic pancreatitis patients with a symptomatic fibrotic PD stricture (located proximal from the spine), for which endoscopic drainage is considered.
Epistemonikos ID: 389e7887e47a2fd0ff215abe09cc2195b198ca4b
First added on: Aug 23, 2024