Neurological Soft Signs in Neurodegenerative Dementias

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2022
The goal of this observational study is to investigate the prevalence of Neurological Soft Signs (NSS) in various categories of dementia patients compared to matched controls. The main questions it aims to answer are: * Does the prevalence of NSS significantly differ among patients with neurodegenerative dementias compared to controls? * Are NSS associated with neuropsychiatric alterations in dementia patients? * Do NSS correlate with cognitive screening tools? * Do NSS increase over time in patients with neurodegenerative dementias? Participants will undergo assessments including: * Evaluation of NSS using the Heidelberg scale * Neuropsychiatric assessments * Cognitive screening using the Mini-Mental State Examination (MMSE) and Frontal Assessment Battery (FAB) Researchers will compare dementia groups (Alzheimer\'s disease, Frontotemporal dementia, Corticobasal syndrome and Lewy body dementia) to controls to determine differences in NSS prevalence. Additionally, associations between NSS and neuropsychiatric symptoms, as well as cognitive performance, will be explored.
Epistemonikos ID: d0f2065dfd2618f667dd197e3b51e5b73b44ea3e
First added on: May 15, 2024