Effect of ketotifen on the ultrastructure of the erythrocytic stages of Plasmodium yoelii.

Authors
Category Primary study
JournalThe Southeast Asian journal of tropical medicine and public health
Year 1990
The effect on the morphology of Plasmodium yoelii of ketotifen treatment was different from that of chloroquine and other antimalarial drugs. Following administration of a low dosage of ketotifen, the parasite first developed a multilamellate pellicular complex which resembled a medullary sheath and then developed vacuoles and cavitations. The development of large multilamellate whorls consisting of a pellicular structure enclosing cytoplasm was the typical change which occurred.
Epistemonikos ID: d056b7f27fd8e73ab1f7980dbffcbd19b756302b
First added on: Sep 22, 2024