The effects of preventive interventions for constipation during breast cancer chemotherapy: a pilot study

INTERVENTION: the instruction of the constipation prevention method (massage, exercises, excretion method)for one week on the chemotherapy day before. the instruction of the constipation prevention method (massage, exercises, excretion method) on the next chemotherapy day. CONDITION: Constipation with breast cancer therapy PRIMARY OUTCOME: Constipation; (Score of Constipation assessment scale) SECONDARY OUTCOME: defecation; use of laxative; QOL ; mood and emotional state ; sleep activity rhythm; Action INCLUSION CRITERIA: all the following conditions (1)Admit into the Kyoto University hospital for breast cancer treatment and receiving chemotherapy (2)Control emesis by the 5‐HT3 receptor antagonist which include Ondansetron, Granisetron, Tropisetron, Palonosetron, before chemotherapy. (3)Performance Status 0 or 1 (4)able to defecate with normal digestive organ and trunk function (5)Signed informed consent for this study