Identification of an erm(A) erythromycin resistance methylase gene in Streptococcus pneumoniae isolated in Greece.

Category Primary study
JournalAntimicrobial agents and chemotherapy
Year 2001
In a serotype 11A clone of erythromycin-resistant pneumococci isolated from young Greek carriers, we identified the nucleotide sequence of erm(A), a methylase gene previously described as erm(TR) in Streptococcus pyogenes. The erm(A) pneumococci were resistant to 14- and 15-member macrolides, inducibly resistant to clindamycin, and susceptible to streptogramin B. To our knowledge, this is the first identification of resistance to erythromycin in S. pneumoniae attributed solely to the carriage of the erm(A) gene.
Epistemonikos ID: cfaa89c492890d01bb41f0b5c0e6267718fac088
First added on: Jan 04, 2023