Prospective Evaluation of Self-Testing to Increase Screening

Regularly attending for Pap test cervical cancer screening in a clinic is often unfeasible and/or unacceptable to many women. Using mailed self‐sampling kits to test for high‐risk human papillomavirus (HPV), the virus that causes cervical cancer, may overcome multiple barriers to clinic‐based screening. This study is a randomized controlled trial to compare the effectiveness of three outreach interventions to increase primary screening participation and clinical follow‐up among underscreened women a in a safety net health system. The three strategies that will be evaluated are: 1) telephone recall; 2) telephone recall with mailed self‐sample HPV testing kits; and 3) telephone recall with mailed self‐sample HPV testing kits and patient navigation.