Can virtual reality-based meditation help reduce anxiety and depression in patients newly diagnosed with acute leukemia?

INTERVENTION: Randomization: Random assignment to the intervention group and control group will be performed by SPSS 24.0 at a proportion of 1:1. The 70 generated codes will be written on the same sized paper and the paper will be placed in opaque, sealed, and sequentially numbered envelopes. A participant receives a numbered envelope after the qualified initial assessment. The paper showing “1” means that the participant is assigned to the control group, and “2” means that the participant is assigned to the intervention group. Control group: The control group will receive conventional care alone, including general care, psychological care, and health education. General care: limiting activity depending on patients condition to prevent bleeding, preventing blocking and infection from a peripherally inserted central catheter, protective quarantine used to prevent infection in patients, oxygen inhalation to prevent symptoms caused by anemia, adequate nutrition intake, monitoring changes of patients' vital signs and side‐effect caused by chemotherapy. Psychological care: developing a good relationship with patients, identifying patients' negative emotions, and enlightening them. Health education: assisting patients to build up to perception and cognition of disease through imparting knowledge. Intervention group: In addition to conventional care, the VR combined with meditation intervention is offered to patients in the intervention group. During the intervention, patients experience a sense of immersion through a VR device delivering meditation guidance, background music, and images. We selected 14 different VR 3D videos (about 20 minutes) which are freely downloaded from the Internet, CONDITION: Prevention of anxiety and depression during induction chemotherapy in previously untreated patients newly diagnosed with acute leukemia ; Mental and Behavioural Disorders PRIMARY OUTCOME: ; 1. Anxiety is measured using State Anxiety Inventory at baseline and post‐intervention (2 weeks); 2. Depression is measured using the Center for Epidemiological Studies Depression Scale at baseline and post‐intervention (2 weeks); SECONDARY OUTCOME: Quality of life is measured using The Functional Assessment of Cancer Therapy‐Leukemia Questionnaire at baseline and post‐intervention (2 weeks). INCLUSION CRITERIA: 1. Newly diagnosed with acute leukemia, including acute myeloid leukemia and acute lymphocytic leukemia 2. No relevant previous treatment 3. Aged 18 years and over 4. Normal cognition and comprehension 5. Karnofsky Performance Status >60