Development of an Adaptive Treatment for Weight Loss in People With Prediabetes

Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2021
This 16-week study will use an experimental approach called the Sequential Multiple Assignment Randomized Trial to help determine which combination and sequence of weight loss program features are most effective in people who are at risk for type 2 diabetes. Participants in the study will be initially randomized to consume either a high or reduced carbohydrate diet. After 4 weeks, participants will be identified as Responders (greater than or equal to 2.5% weight loss) or Non-Responders (less than 2.5% weight loss). Responders will continue with their initial randomized group for the remainder of the trial. Non-responders will be re-randomized to 2nd stage interventions of either including additional exercise counseling and training or beginning a time restricted eating protocol for the remainder of the trial.
Epistemonikos ID: cf45f6eed77430593afe8b1b6dd48b3df9cf4f6c
First added on: May 08, 2024