Study on the clinical efficacy and mechanisms of acupoint hypersensitivity in the treatment of primary insomnia with acupuncture intervention

Authors
Category Primary study
Registry of TrialsInternational Traditional Medicine Clinical Trial Registry
Year 2025
INTERVENTION: Sensitized Acupoint Acupuncture Group:(1) Acupoints: Juque, Xinyu Shuang, Fengchi Shuang, Taiyang Shuang. (2) Positioning: Refer to the 2021 National Standard of the People's Republic of China (GB/T 12346‐2021) "Acupuncture Point Name and Positioning" (GB/T 40997‐2021) "Extrameridian Strange Acupuncture Point Name and Positioning". Juque (RN14): in the upper abdomen, 6 inches above the middle of the umbilicus, on the anterior midline. Xinyu (BL15): On the back, under the spinous process of the 5th thoracic vertebra, 1.5 inches next to the posterior midline. Fengchi (GB20): In the depression between the upper end of the sternocleidomastoid muscle and the upper end of the trapezius muscle in the neck, under the occipital bone. Sun (EX‐HN5): In the depression of the head, between the tip of the eyebrow and the outer canthus of the eye, about a horizontal finger (middle finger) backward. (3) Treatment operation: 0.25mm×40mm millineedles are selected, both are pierced 5 15 mm, and then the insertion and twisting are performed to flatten and compensate for the la Xtechnique, with a lifting and insertion range of 0.3 0.5 cm, a frequency of 60 90 times/min, a twisting angle of 90° 180°, a frequency of 60 90 times/min, and a needle retention for 30 minutes. (4) Treatment cycle: 3 times a week for a total of 4 weeks.;Sham acupuncture group:(1) Acupoint take: 4 non‐meridian and non‐acupuncture points are selected (2) Positioning: Referring to [50], the false needle point is set 2 cm next to the real needle point, but not on any known acupuncture points and meridians. Ineffective point 1: Located on the anterior midline, 2 inches below the xiphoid process, 1 inch apart. Bilateral ineffective acupoint 2: Located on the back, under the spinous process of the 5th thoracic vertebra, 4 CONDITION: L1‐7A0 Primary insomnia PRIMARY OUTCOME: Pittsburgh Sleep Quality Index; SECONDARY OUTCOME: Self‐Rating Anxiety Scale;Self‐Rating Depression Scale;mechanical pain threshold;Polysomnography;Heart Rate Variability; INCLUSION CRITERIA: (1) Meets the diagnostic criteria for primary insomnia disorder; (2) Age between 18 and 80 years, gender; (3) No communication or cognitive impairments; (4) No use or discontinuation of anti‐anxiety or other psychotropic medications within the past month; (5) No major somatic diseases; (6) Voluntarily accepts the study content and is able to complete all assessments and polysomnography; (7) Signed the informed consent form before the start of the study; (8) Patients with mild to moderate insomnia, as indicated by a Pittsburgh sleep quality inde Xscore of 7‐16.
Epistemonikos ID: cdd7d855241cdbf3554fc69bdac90051935a6a6a
First added on: Jan 24, 2026