A randomized controlled trial of microecological changes of salicylic acid resurfacing andtopical antibiotics in acne vulgaris

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: Control group:Apply topical fusidic acid (Hong Kong Aomei Pharmaceutical) evenly over the entire face twice daily, using approximately 1 g per application. Follow‐up visits should be scheduled every two weeks, for a total of five follow‐up visits.;Observation group:Salicylic acid peel (Boleda Supramolecular Salicylic Acid), with one treatment every 14 days (for a total of 4 treatments) and one follow‐up visit every 14 days (for a total of 5 follow‐up visits); CONDITION: Acne vulgaris. PRIMARY OUTCOME: Overall assessment by researchers (IGA);Count of inflammatory papules and comedoes lesions; SECONDARY OUTCOME: dermatogram;Microecological examination; INCLUSION CRITERIA: 1.Clinically diagnosed as mild to moderate acne vulgaris (in accordance with the diagnostic criteria of Chinese Dermatology and Venereology (Clinical Edition) and pillsbury acne grading criteria). 2.The average age was between 18 and 40 years old, regardless of gender; 3.Dermatoscopy is consistent with acne vulgaris; 4.Voluntarily agree to participate in the study and sign the informed consent;
Epistemonikos ID: cdd1550a02206ddac7796d4808a25155efa21d94
First added on: Oct 08, 2026