Healing effects of Er: YAG laser on peri-implant mucositis and peri-implantitis: a clinical randomized controlled trial

INTERVENTION: Test group 1: 18patients 2: Er: YAG laser beam is delivered into the pocket of implant using PS600T tip at 30mJ/25pps under water irrigation. Control group 1: 18 patients 2: 2% minocycline ointment is delivered into the pocket of implant. CONDITION: Peri‐implant mucositis and peri‐implantitis PRIMARY OUTCOME: Cytokine expression levels in peri‐implant crevicular fluid SECONDARY OUTCOME: Species and numbers of subgingival bacteria INCLUSION CRITERIA: 1.Moderate to severe peri‐implant mucositis and peri‐implantitis. 2.Having probing pocket depth(PPD) equal or greater than 5mm and bleeding on probing(BOP) positive.