Emergence of Azole-Resistant Aspergillus fumigatus from Immunocompromised Hosts in India.

Authors
Category Primary study
JournalAntimicrobial agents and chemotherapy
Year 2018
This prospective study shows that the rate of azole-resistant Aspergillus fumigatus (ARAF) in an immunocompromised Indian patient population with invasive aspergillosis (IA) is low, 6/706 (0.8%). This low rate supports the continued use of voriconazole as the first line of treatment. However, the ARAF isolates from India in this study exhibited three kinds of unreported cyp51A mutations, of which two were at hot spots, G54R and P216L, while one was at codon Y431C.
Epistemonikos ID: cbcbacad6a0b769b2eebcd490aa65f178f527bd2
First added on: Jan 07, 2023