Interaction Between St John's Wort and Metformin?

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2013
The goal of the study is to examine the difference of the pharmacokinetics of metformin with and without a 3 weeks pretreatment of St John\'s Wort. Furthermore secondary objectives include changes in GLP-1, C-peptide, serum-insulin and plasma-glucose during an oral glucose tolerance test, changes in OCT1 mRNA in plasma and changes in leptin and lipid-profile following this possible interaction.
Epistemonikos ID: ca2cee718741d9260f7c8d9fcf277aff05a90b16
First added on: May 11, 2024