Preemptive Administration of the Biased µ-Opioid Agonist Oliceridine for Postoperative Respiratory Depression in Obese Laparoscopic Patients

INTERVENTION: Intervention group:Oliceridine fumarate injection, 1.5 mg, should be administered via slow intravenous injection (injection time >= 30 seconds). According to the Chinese drug instructions approved on April 28, 2023, the initial dose of oxelidine is fixed at 1.5 mg, with no adjustment based on body weight.;Control group:Sufentanil citrate injection, at a dose of 0.1 µg/kg (based on actual body weight), is administered via slow intravenous injection.; CONDITION: Respiratory depression after laparoscopic surgery PRIMARY OUTCOME: The incidence of postoperative respiratory depression within 24 hours; SECONDARY OUTCOME: Numeric Rating Scale (NRS) pain scores at rest and during coughing at 1 h, 2 h, 6 h, 12 h, and 24 h postoperatively.;Incidence of postoperative nausea and vomiting (PONV) within 24 hours after surgery;Time to first flatus and time to first defecation within 24 hours postoperatively;Total rescue opioid consumption within 24 hours postoperatively;Ramsay sedation score at 24 hours postoperatively;Quality of Recovery‐15 (QoR‐15) scores at 1 h, 2 h, 6 h, and 12 h postoperatively;Incidence of breakthrough pain; INCLUSION CRITERIA: 1. Aged 18‐65 years; 2.Body mass inde X(BMI) >= 28.0 kg/m^2; 3.Elective laparoscopic surgery under general anesthesia; 4. Anticipated duration of surgery >=1 hour; 5. American Society of Anesthesiologists (ASA) physical status classification I‐III; 6. Provision of written informed consent prior to any study‐related procedures;