Effectiveness of homoeopathic medicine in improving symptoms of allergic rhinitis in patients with hypothyroidism

INTERVENTION: Intervention1: Individualized Homoeopathic Medicine: After enrollment Patients are randomly allocated in to Group A individualized homoeopathic medication or group B placebo For group A patients appropriate potentized individualized homoeopathic medicine will be administered in minimum dose in appropriate potency according to the need of the case Medicine will be administered orally Repetition of the medicine and change of potency or remedy if required will be based on clinical assessment and homoeopathic principles during follow‐up Participants in the intervention arm will receive individualized homoeopathic medicine for a period of 6 months Rescue medication will be permitted in both groups as needed The number of rescue medication doses consumed will be recorded throughout the study Control Intervention1: Placebo: After enrollment Patients are randomly allocated in to Group A individualized homoeopathic medication or group B placebo Participants randomized to the control group will receive placebo identical in appearance and packaging Placebo will be administered orally The placebo will consist of saccharum lactis and will be administered according to the same dosing schedule as the intervention group Participants in control group will recieve placebo for a duration of 6 months Rescue medication will be permitted in both groups as needed The number of rescue medication doses consumed will be recorded throughout the study CONDITION: Health Condition 1: J309‐ Allergic rhinitis, unspecified Health Condition 2: E039‐ Hypothyroidism, unspecified PRIMARY OUTCOME: Improvement of clinical severity of allergic rhinitis measured using Reflective Total Nasal Symptom ScoreTimepoint: Every month for six months SECONDARY OUTCOME: Reduction in serum total IgE level ; Timepoint: At baseline 3rd month and 6th month Reduction in serum TSH levelTimepoint: At baseline 3rd month and 6th month INCLUSION CRITERIA: Clinically diagnosed cases of allergic rhinitis Patients with serum IgE level above 150 IU per ml Patients having increased TSH level above 4.50mIU per L