The Application of Non-invasive Ventilation in the Treatment of ARDS Secondary to Severe Acute Respiratory Syndrome and Its Effective Factors

Objective:To investigate the effectiveness of non-invasive positive pressure ventilation (NPPV) in the management of ARDS secondary to severe acute respiratory syndrome and its effective factors. Methods: 1. SARS patients were divided into two groups: NPPV group and invasive ventilation (IV) group. 2. The cause of NPPV failure and the prognosis of the IV group were investigated. Results: 1.There was no differentce between the two groups in gender and age composition. 2.The ratio of medical workers/non- medical workers and the Oxygen Index(OI) in NPPV group was 8/3 and (162.3±27.4)mmHg, higher than that in the IV group which was 1/9 and(94.4±36.8)mmHg(both P0.01), but the ratio of basic disease/ non-basic disease and the respiratory rate in NPPV group was 1/10 and(33.5±7.1)times/min, lower than those in the IV group which was 5/5 and (38.8±3.4)times/min(both P0.05). OI was the mild risk factor of the failed NPPV(OR =0.94, P0.05), while the ratio of medical workers/non- medical workers was the strong risk factor of the failed NPPV(OR =57.79, P0.05). Conclusions: NPPV may be used to manage ARDS secondary to severe acute respiratory syndrome. The better the patient fit to NPPV, the higher rate of success.