Textural Research on Key Information of Chaihu Guizhitang

Chaihu Guizhitang is one of the classical formulas in the Catalogue of Ancient Classical Formulas （the second batch）. Through extensive searching and systematic review of ancient medical books on Chaihu Guizhitang， this study summarized the key information of this formula， which encompassed the origin and development， medicinal composition， original plants and processing， dosage， preparation method， usage， compatibility， and indications. A total of 173 valid data entries were obtained， involving a total of 97 ancient books of traditional Chinese medicine. Chaihu Guizhitang is first recorded in ZHANG Zhongjing's Treatise on Cold Damage and consists of nine herbs： Bupleuri Radix， Scutellariae Radix， Cinnamomi Ramulus， Paeoniae Alba Radix， Ginseng Radix et Rhizoma， Pinelliae Rhizoma， Glycyrrhizae Radix et Rhizoma， Rhizoma Zingiberis Recens， and Jujubae Fructus. In ancient medical books， this formula has synonyms such as Chaihu Jia Gui Tang， Chaihu Jia Guizhitang， and Guizhi Chaihu Ge Ban Tang. The medicinal composition of this formula recorded in ancient medical books is basically consistent with that of the original formula， and it is thus recommended that the composition of the original formula should be followed in the current clinical application. The original plants of the herbal medicines in this formula are in accordance with those in the Pharmacopoeia of the People's Republic of China （2020 edition）. In terms of processing methods， Pinelliae Rhizoma processed with ginger， and Glycyrrhizae Radix et Rhizoma is stir-fried. Other herbal medicines in this formula are used with the raw materials. According to the record in the Treatise on Cold Damage， Chaihu Guizhitang is mainly used to treat diseases involving Greater Yang and Lesser Yang. Ancient medical books record that this formula can treat sudden pain in the heart and abdomen， cold abdominal colic， delirium， malaria， thermal imbalance of kidney Qi， and motive Qi. Considering modern medication practice， it is recommended that Chaihu Guizhitang is composed of 14.92 g Bupleuri Radix， 5.60 g Scutellariae Radix， 5.60 g Cinnamomi Ramulus， 5.60 g Paeoniae Alba Radix， 5.60 g Ginseng Radix et Rhizoma， 5.60 g Rhizoma Zingiberis Recens， 4.66 g Pinelliae Rhizoma， 3.73 g Glycyrrhizae Radix et Rhizoma， and 4.30 g Jujubae Fructus， which should be decocted with 1 400 mL water to reach a volume of 600 mL. The decoction should be taken warm after meals， 200 mL each time， three times a day.