Homeopathy on mental health care

INTERVENTION: D27.505.954.427.700 E02.190.388 Experimental group: 64 patients, women, and men from 18 to 70 years‐old, who are on long‐term benzodiazepines and antidepressants in primary care, without a psychiatric evaluation assessment in the 12 months preceding enrollment, will be treated with individualized homeopathy according to Organon.modus protocol and psychotropic medication, as needed. Control group:64 patients, women, and men from 18 to 70 years‐old, who are on long‐term benzodiazepines and antidepressants in primary care, without a psychiatric evaluation assessment in the 12 months preceding enrollment, will be treated with indistinguishable placebo and psychotropic medication, as needed CONDITION: Depressive episodes; Other anxiety disorders ; F32 ; F41 F00‐F99 PRIMARY OUTCOME: Statistically significant mental health score improvement in the experimental group as compared to control group, assessed by the mental component of the 12‐Item Short‐Form Health Survey (SF‐12) at month 12 SECONDARY OUTCOME: 12‐Item Short‐Form Health Survey mental and physical scores, monthly assessed Adverse Event incidence Daily dose of psychotropic medication, monthly assessed DSM‐5 Self‐Rated Level 1 Cross‐Cutting Symptom Measure—Adult, monthly assessed Number of psychotropic medicines daily prescribed, monthly assessed Treatment response rate, defined as an equal or greater to 50% reduction in DSM‐5 Self‐Rated Level 1 Cross‐Cutting Symptom Measure—Adult basal score, monthly assessed INCLUSION CRITERIA: Users of the Basic Health Unit Cidade Aracy (Sao Carlos ‐ Sao Paulo/Brazil), who are on antidepressants; and/or benzodiazepines; without psychiatric follow‐up in the 12 months prior to inclusion