The effect of oral allicin tablets on aphthous ulcers

INTERVENTION: Intervention 1: Intervention group: The intervention group will receive oral allicin tablets (400 mg, Dineh, Iran) containing 1100 micrograms of allicin. The patient will take 4 allicin tablets daily (every 6 hours) (4.4 mg daily) for 10 days. Intervention 2: Control group: It will be similar to oral allicin tablets but without allicin; 4 time a day (every 6 hours) for 10 days. CONDITION: K12.0 Minor recurrent aphthous stomatitis. ; Recurrent oral aphthae PRIMARY OUTCOME: Healing period. Timepoint: Day of referral (start of use), third, seventh, and tenth after starting use. Method of measurement: If both the pain level on the visual analog scale is 1 cm or less and the lesion size is 1 mm or less, the lesion is considered healed. Patients are taught to determine the intensity of their pain based on a visual analogue scale. Patients will record their pain in a checklist 3 times a day after each meal and lesions with a pain value of 1 cm or less will be considered healed. Timepoint: Day of referral (start of use), third, seventh, and tenth after starting use. Method of measurement: Using a visual analog scale; in which the patient marks their pain level from 0 to 10 on a 10‐centimeter line on the day of the visit, third, seventh, and tenth day. The distance between the 2 outer edges of the ulcer border in mm; lesions less than 1 mm in diameter will be considered healed. Timepoint: Day of referral (start of use), third, seventh, and tenth after starting use. Method of measurement: To determine the wound size, the researcher measures the distance between the 2 outer edges of the wound border in millimeters using a calibrated dental probe (D&G, Pakistan). INCLUSION CRITERIA: Patients with minor recurrent aphthous stomatitis Men and women aged 18 to 50 who are able to follow a doctor's advice Willing to participate in the study and not use painkillers during it Patients with aphthous lesions on the lips, buccal mucosa, floor of the mouth, and tongue Has an aphthous ulcer (up to 48 hours have passed since the lesion formed) smaller than 10 mm