Examination of respiratory mechanics with trunk inclination in obese and non-obese ARDS patients

Authors
Category Primary study
Registry of TrialsANZCTR
Year 2023
INTERVENTION: Intervention ‐ Trunk inclination (40 degree and zero degree) in a randomized cross over design in obese and non‐obese mechanically ventilated ARDS patients. This will be done using the ICU bed controls by the treating physician Each inclination will be done for 15 minutes before the measurements (lung mechanics and blood gases) are done. Each inclination (either 40 degree and zero degree) will be maintained for 15 minutes and both inclinations will be tested within the same session CONDITION: ARDS; ; ARDS Diet and Nutrition ‐ Obesity Respiratory ‐ Other respiratory disorders / diseases PRIMARY OUTCOME: Partition respiratory mechanics ‐driving pressure using the ventilator and the method described by Stenqvist et al (Intensive Care Med (2015) 41:1110–1113)[15 minutes post intervention completion] Partition respiratory mechanics ‐Elastance using the ventilator and the method described by Stenqvist et al (Intensive Care Med (2015) 41:1110–1113)[15‐minute post intervention completion ] SECONDARY OUTCOME: Gas exchange (Arterial blood gas‐ PaCo2)[15 minutes post intervention completion ] Gas exchange (Arterial blood gas‐ PaO2)[15 minutes post intervention completion ] Gas exchange (Arterial blood gas‐ pH)[15 minutes post intervention completion ] INCLUSION CRITERIA: diagnosis of moderate or severe ARDS (Berlin definition), deep sedation, muscle paralysis, volume controlled mechanical ventilation
Epistemonikos ID: c58449566cbc8e4b0c66d13e8f400480d6e195a6
First added on: Aug 26, 2024