Nutrient Supplementation Influences Mitochondria Adaptation

Twenty‐four well trained runners (VO2max 60.73.7 ml O2 Kg‐1 min1) completed a six week block randomized controlled intervention period. Subjects were randomly assigned to either PRO‐CHO or CHO and matched in pairs for gender, age, VO2max, training and performance status. The PRO‐ CHO group ingested a protein beverage (0.3g kg‐1) before and protein‐carbohydrate beverage (0.3g protein kg‐1 and 0.1g carbohydrate kg‐1) after each exercise session. The CHO group ingested energy matched carbohydrate. Post‐absorptive muscle biopsies were obtained pre and post intervention for analysis HAD, CS and PGC‐1. Subjects completed two physical tests 6 km performance test (pre, week 1 and week 6) and aVo2max test (pre and post intervention).