Difference in Efficacy of Acupuncture and Lianazonamide Pyridine for Ulcerative Colitis: Meta Analysis

Objective: Systematic evaluation of the difference in efficacy of acupuncture and liazsulfonamide pyridine (SASP) in treatment of ulcerative colitis (UC) Method: Computer retrieval of the Chinese Journal Full Text Database, Vip Database, Pubmed Database, Embase Database and Science Direct Database, collected June 2001 to June 2015 published during the Article on randomized controlled trials (RCT) for comparing acupuncture with SASP treatment UC and screening of the literature according to incorporation and exclusion criteria. Data extraction of the final inclusion literature and quality evaluation using the Acupuncture RCT Articles Specification Element Sheet. Fruit: 25 RCT literature, 2,166 patients The literature quality evaluation showed that the included RCT articles had an average quality score of 24.48 (61.2 per cent), with the highest score being a description of intervention detail (8.32,69.33 per cent); the inclusion of RCT all had methodological problems and had a moderate likelihood of yielding a bias .Meta analysis showed that, compared with SASP, acupuncture Improve the short-term effective effectiveness of treatment (OR= 5.23,95% CI [3.88,7.05], Z=10.83, P≈ 0.05) and long-term effective (OR=4.15,95% CI [1.87,9.20], Z=3.51, P≈ 0.05); acupuncture significantly improved tumor necrosis factor content after treatment of subjects (SMD=1.78,95%) [ 0.40,3.15], Z=2.54, P^0.05), IgG content (SMD=2.05,95% C I [0.24,3.86], Z=2.22, P^0.05) and GA content (SMD=4.27,95% CI [1.11,7.42], Z=2.65, P^0.05), but not the IgM content ( SMD=0.13,95% CI [-0.15,0.42], Z=0.90, P+0.05). Conclusion: Acupuncture treatment for UC is better than SASP, but due to some deficiencies in methodological quality, the above conclusions have yet to be developed more rigorous, large sample, multi-center randomized controls. test to confirm.