fMRI Study on the Therapeutic Efficacy and Central Mechanisms of Tuina for Primary Dysmenorrhea with the Cold Congestion and Blood Stasis Pattern

Authors
Category Primary study
Registry of TrialsInternational Traditional Medicine Clinical Trial Registry
Year 2026
INTERVENTION: Experimental Group:Tuina;Control Group:Oral Ibuprofen; CONDITION: Primary Dysmenorrhea PRIMARY OUTCOME: Visual Analogue Scale; SECONDARY OUTCOME: Co XMenstrual Symptom Scale;Pittsburgh Sleep Quality Index;Brain Magnetic Resonance Imaging;Self‐Rating Anxiety Scale;Self‐Rating Depression Scale;TCM Syndrome Score; INCLUSION CRITERIA: 1) Nulliparous women aged 15 to 30 years with primary dysmenorrhea (PD);2) Meeting the Western medical diagnostic criteria for primary dysmenorrhea;3) Conforming to the TCM diagnostic criteria for dysmenorrhea of the cold congelation and blood stasis pattern;4) Having a regular menstrual cycle (28±7 days);5) No organic pelvic lesions identified by pelvic examination, pelvic ultrasonography or laparoscopy;6) Suffering from persistent menstrual pain with a Visual Analogue Scale (VAS) score of =4;7) No analgesics taken within 24 hours prior to magnetic resonance imaging (MRI) scanning, no analgesics, sedatives or hormonal drugs administered within one week before treatment, and no oral contraceptives used within three months;8) Voluntarily participating in the clinical study and providing signed informed consent.
Epistemonikos ID: c33fafd53719ce63ec55047a1836e2fa65e13319
First added on: Aug 10, 2026