Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Pregnancy Outcomes of Infertility Patients Undergoing in Vitro Fertilization

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2025
The goal of this clinical trial is to learn if Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) enhance outcomes of in vitro fertilization (IVF). It will also learn about the safety of taVNS. The main questions it aims to answer are: Does taVNS improve the clinical pregnancy rate of infertility patients undergoing IVF? What medical problems do participants have when using the taVNS device? Researchers will compare the taVNS to the sham transcutaneous auricular vagus nerve stimulation (a look-alike device that produces a sub-threshold therapeutic stimulus and functions as a sham stimulus) and blank control to see if the taVNS device works to enhance outcomes of IVF. Participants will: Use the device a total of 2 hours daily, with the sessions divided into four parts, each lasting 30 minutes. At least one of these periods occur within 2 hours before bedtime. Visit the clinic according to the scheduled treatment time points of IVF. Keep a diary of their adverse events and the number of times they use the device
Epistemonikos ID: c2997c4f19535dfb19f683fc48902d06646c3566
First added on: Jan 01, 2025