Efficacy of topical curcumin on mild to moderate idiopathic carpal tunnel syndrome

INTERVENTION: Intervention 1: Intervention group: Curcumin topical ointment is a turmeric extract and is manufactured by Exir Nanosina.Twice a day in the morning and at the night, 12 hours interval, in the anterior of wrist is rubbed. duration of treatment is 8‐week.The ointment should not be washed up to 2 hours after using the ointment. Intervention 2: Control group: The placebo is an ointment that has a shape, color and concentration similar to curcumin ointment. The tubes are in the same shape.Produced by Exir Nanosina company.The frequency of use, dose and duration of use is the similar to intervention group. CONDITION: Carpal tunnel syndrome. ; Carpal tunnel syndrome PRIMARY OUTCOME: Boston questionnaire score and severity of pain according to VAS. Timepoint: Before intervention and Eighth week after treatment. Method of measurement: Boston questionnaire and VAS. EMG‐NCV parameters changes. Timepoint: Before intervention and Eighth week after treatment. Method of measurement: Electrodiagnostic. INCLUSION CRITERIA: Female patients aged 18‐65 years old completed the informed consent form Sign and symptoms of carpal tunnel syndrome: at least two symptoms or one symptom and one sign including: pain, paresthesia, hypoesthesia, numbness, positive phalen or tinel test Electrodiagnostic evidence suggestive of mild to moderate idiopathic carpal tunnel syndrome